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Planta Med 1994; 60(3): 267-271
DOI: 10.1055/s-2006-959473
Paper

© Georg Thieme Verlag Stuttgart · New York

Constituents of the Egyptian Centaurea scoparia; Chlorinated Guaianolides of the Aerial Parts

Diaa Youssef, August W. Frahm
  • Pharmazeutisches Institut der Universitát, Hermann-Herder-Str. 9, D-79104 Freiburg i.Br., Federal Republic of Germany
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Publication History

1993

1993

Publication Date:
04 January 2007 (online)

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Abstract

A new chlorine-containing guaianolide, chloroscoparin, was isolated from the ethanol extract of the aerial parts of Centaurea scoparia Sieb. together with three known chlorine-containing guaianolides. The structures of the isolated compounds were elucidated by spectroscopic methods including 1H-NMR-, 2D 1H-1H COSY-, 13C-NMR-, APT-, DEPT-, HETCOR-, long-range-HETCOR-, 2D INADEQUATE-, and mass spectra. The relative configuration was determined by 2D-NOESY studies. New NMR data for the known compounds are reported.

Key words

Centaurea scoparia Sieb. - Asteraceae - chlorine-containing guaianolides

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