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Planta Med 2002; 68(10): 936-939
DOI: 10.1055/s-2002-34928
Letter
© Georg Thieme Verlag Stuttgart · New York

Component of Zingiber officinale that Improves the Enhancement of Small Intestinal Transport

Kazunori Hashimoto1 , Kazuko Satoh1 , Pin Murata1 , Bunsho Makino1 , Iwao Sakakibara1 , Yoshio Kase1 , Atsushi Ishige1 , Masami Higuchi1 , Hiroshi Sasaki1
  • 1Kampo & Pharmacognosy Laboratory, Tsumura & Co., Ibaraki 300-1192, Japan
Further Information

Publication History

Received: March 15, 2002

Accepted: June 8, 2002

Publication Date:
21 October 2002 (online)

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Abstract

6-Shogaol, a constituent of Zingiber officinale, improved carbachol-induced accelerated small intestinal transit in vivo, as well as improving longitudinal muscle contraction induced by low-frequency electrical stimulation of the isolated guinea pig small intestine in vitro. In addition, 6-shogaol ameliorated BaCl2-induced hyperperistalsis of the small intestine in vivo.

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Ph. D. Kazunori Hashimoto

Kampo & Pharmacognosy Laboratory

Tsumura & Co.

3586 Yoshiwara

Ami-machi

Inashiki-gun

Ibaraki 300-1192

Japan

Fax: +81-298-89-3825

Email: hashimoto_kazunori@ mail.tsumura.co.jp

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