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Horm Metab Res 1982; 14(6): 284-287
DOI: 10.1055/s-2007-1018996
© Georg Thieme Verlag, Stuttgart · New York

Insulin and C-Peptide Levels in Obese Patients with Polycystic Ovaries

R. Pasquali, S. Venturoli2 , R. Paradis2 , M. Capelli1 , M. Parenti, N. Melchionda
  • Institute of Internal Medicine, s. orsola Hospital, University of Bologna, Bologna, Italy
  • 1Central Laboratory, s. orsola Hospital, University of Bologna, Bologna, Italy
  • 2Institute of Reproductive Physiology and Pathology, s. orsola Hospital, University of Bologna, Bologna, Italy
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Publication History

1981

1981

Publication Date:
23 April 2008 (online)

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Summary

We studied two groups of obese patients, 16 affected by polycystic ovaries (OB-PCO) and 16 with simple obesity (OB), matched for age, relative weight and glucose values during oral glucose tolerance test. OB-PCO patients showed higher basal IRI levels and highere glucose stimulated IRI and CPR sezum levels. According to these results, hyperinsulism appears to be a common feature of PCO patients, relatively independent of the presence of obesity. Possible mechanisms are discussed.

Key-Words:

Obesity - Polycystic Ovaries - Insulin - Insulin Resistance - Insulin Secretion - C-Peptide

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