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Horm Metab Res 1984; 16(1): 53-54
DOI: 10.1055/s-2007-1014693
Short Communications

© Georg Thieme Verlag, Stuttgart · New York

Effect of Methadone on TSH and Thyroid Hormone Secretion

P. P. Vescovi, G. Gerra, G. Rastelli, G. P. Ceda, G. Valenti
  • Istituto di Clinica Medica Generale e Terapia Medica dell'Università degli Studi di Parma, Parma, Italy
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Publication History

1982

1983

Publication Date:
14 March 2008 (online)

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Summary

The hypothalamus-pituitary-thyroid function was studied in 15 male patients on chronic methadone treatment (40 mg/day).

No significant variations of TSH, T4, T3 and rT3 levels were documented, either in basal conditions or after TRH stimulation; however a reduced TSH pituitary response was recorded in some patients (6 out of 15).

Key-Words:

TSH - Thyroid Hormones - TRH - Opioid System - Methadone - Drug-Addicts

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