Isolierung des antiphlogistischen Wirkprinzips von Epilobium angustifolium

Alois Hiermann; Monika Reidlinger; Heinz Juan; Wolfgang Sametz

doi:10.1055/s-2006-960117

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Planta Med 1991; 57(4): 357-360
DOI: 10.1055/s-2006-960117

Papers

Isolierung des antiphlogistischen Wirkprinzips von Epilobium angustifolium

Isolation of the Antiphlogistic Active Principle from Epilobium angustifolium Alois Hiermann¹ ^, [3] , Monika Reidlinger² , Heinz Juan² , Wolfgang Sametz²

¹Institut für Pharmakognosie, Universität Graz, Universitätsplatz 4, A-8010 Graz, Austria
²Institut für experimentelle und klinische Pharmakologie, Universität Graz, Universitätsplatz 4, A-8010 Graz, Austria

Further Information

Publication History

1990

Publication Date:
05 January 2007 (online)

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Abstract

From the leaves of Epilobium angustifolium L. (Onagraceae) an antiphlogistic principle was isolated and identified as myricetin 3-O-β-D-glucuronide. This novel flavonoid exhibited a very strong anti-inflammatory effect on carrageenan-induced edema in the rat hind paw (more than ten times more effective than indomethacin) and an inhibitory effect on prostaglandin biosynthesis (as effective as indomethacin).

Key words

Epilobium angustifolium - antiphlogistic principle - anti-inflammatory action - inhibition of prostaglandin biosynthesis - myricetin 3-O-β-D-glucuronide

3 Meiner Mutter zum 85. Geburtstag gewidmet

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