Chemical Composition and Anti-Inflammatory Activity of the Volatile Fractions from the Bark of Eight Mexican Bursera Species

 

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Abstract

The volatile fractions from the bark of eight species of Mexican Bursera were obtained using steam distillation and were subjected to tandem GC-MS analysis for identification of the main constituents. The most abundant components of steam volatiles were monoterpenoids from which α-terpineol, terpinen-4-ol, α-thujene, linalool and limonene were most frequently isolated. A series of sesquiterpenes and long-chain hydrocarbons were isolated and identified from the barks of some of the studied species. Some volatiles were assayed for anti-inflammatory activity using the TPA-induced ear edema bioassay in mice. The volatile fraction from Bursera lancifolia was about half as active as indomethacin.

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Prof. Baldomero Esquivel

Instituto de Química de la Universidad Nacional Autónoma de México

Circuito Exterior de Cd. Universitaria

Coyoacán 04510

México

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Email: baldo@servidor.unam.mx