Pharmacopsychiatry 2001; 34(1): 25-26
DOI: 10.1055/s-2001-15190
Original Paper
© Georg Thieme Verlag Stuttgart · New York

Acute and Long-Term Treatment of Catatonia with Risperidone

B. Hesslinger, J. Walden, C. Normann
  • University of Freiburg, Department of Psychiatry and Psychotherapy, Freiburg, Germany
Further Information

Publication History

Publication Date:
31 December 2001 (online)

Catatonia is a rare but difficult-to-treat disorder. Here, we report on the case of a schizophrenic patient who developed several episodes of severe catatonia after suffering from adequately treated Lyme disease with encephalitis. The catatonic stupor was not responsive to typical neuroleptics and benzodiazepines. After the medication was changed to risperidone, there was a dramatic and persistent improvement of the patient's condition. Two relapses during the follow-up period over five years were caused by dose reductions. Risperidone might be a promising drug in the treatment of acute catatonia and in preventing further episodes.

References

  • 1 Bahro M, Kampf C, Strnad J. Catatonia under medication with risperidone in a 61-year-old patient.  Acta Psychiatr Scand. 1999;  99 223-224
  • 2 Barenett W, Sigmund D, Roelcke U, Mundt C. Endomorphes paranoid-halluzinatorisches Syndrom durch Borrelienenzephalitis.  Nervenarzt. 1991;  62 445-447
  • 3 Blumer D. Catatonia and the neurolepics: psychobiologic significance of remote and recent findings.  Comprehensive Psychiatry. 1997;  38 193-201
  • 4 Brown J S. Geographic correlation of schizophrenia to ticks and tick-borne encephalitis.  Schizophr Bull. 1994;  20 755-775
  • 5 Bush G, Fink M, Petrides G, Dowling F, Francis A. Catatonia. II. Treatment with lorazepam and electroconvulsive therapy.  Acta Psychiatr Scand. 1996;  93 137-143
  • 6 Cook E H, Olson K, Pliskin N. Response of organic catatonia to risperidone.  Arch Gen Psychiatry. 1996;  53 82-83
  • 7 Fallon B A, Nields J A. Lyme disease: a neuropsychiatric illness.  Am J Psychiatry. 1994;  151 1571-1583
  • 8 Francis A, Divadeenam K M, Bush G, Petrides G. Consistency of symptoms in recurrent catatonia.  Comprehensive Psychiatry. 1997;  38 56-60
  • 9 Hess A, Buchmann J, Zettl U K, Henschel S, Schlaefke D, Grau G, Benecke R. Borrelia burgdorferi central nervous system infection presenting as an organic schizophrenialike disorder.  Biol Psychiatry. 1999;  45 795
  • 10 Neppe V M. Management with catatonic stupor with L-Dopa.  Clin Neuropharmacol. 1988;  11 90-91
  • 11 Peralta V, Cuesta M J, Serrano J F, Mata I. The Kahlbaum Syndrome: a study of its clinical validity, nosological status, and relationship with schizophrenia and mood disorder.   Comprehensive Psychiatry. 1997;  38 61-67
  • 12 Poyurousky M, Bergmann J, Weizman A. Risperidone in the treatment of catatonia in a schizophrenic patient.  Isr J Psychiatry Rel Sci. 1997;  34 323-324
  • 13 Rankel H W, Rankel L E. Carbamazepine in the treatment of catatonia.  Am J Psychiatry. 1988;  145 361-362
  • 14 Roelcke U, Barnett W, Wilder-Smith E, Sigmund D, Hacke W. Untreated neuroborreliosis: Bannwarth's syndrome evolving into acute schizophrenia-like psychosis. A case report.  J Neurol. 1992;  239 129-131
  • 15 Rohland B M, Carroll B T, Jakoby R G. ECT in the treatment of the catatonic syndrome.  J Affective Disorders. 1993;  29 255-261
  • 16 Rosebush P I, Hildebrand A M, Furlong B G, Mazurek M F. Catatonic syndrome in a general psychiatric inpatient population: frequency, clinical presentation, and response to lorazepam.  J Clin Psychiatry. 1990;  51 357-362

Dr. C. Normann

Universität Freiburg
Abteilung für Psychiatrie und Psychotherapie

Hauptstrasse 5

79104 Freiburg

Germany

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