Inhibitory effect on no production of compounds from Styrax obassia

BS Min; TQ Cao; TM Hung; JA Kim

doi:10.1055/s-0035-1556504

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Planta Med 2015; 81 - PX60
DOI: 10.1055/s-0035-1556504

Inhibitory effect on no production of compounds from Styrax obassia

BS Min ¹, TQ Cao ¹, TM Hung ¹, JA Kim ²

¹College of Pharmacy, Drug Research and Development Center, Catholic University of Daegu, Gyeongbuk 712 – 702, Republic of Korea
²College of Pharmacy, Kyungpook National University, Daegu 702 – 701, Korea

Congress Abstract

Two new benzofurans, 2-(3,4-dimethoxyphenyl)-5-(1,3-dihydroxypropyl)-7-methoxybenzofuran (1), and 2-(3,4-methylenedioxyphenyl)-5-(3-hydroxymethyletoxy-1-hydroxypropyl)-7-methoxybenzofuran (2) along with eleven known compounds as syringaresinol (3), lariciresinol (4), pinoresinol (5), epi-pinoresinol (6), 2-(3,4-methylenedioxyphenyl)-5-(1,3-dihydroxypropyl)-7-methoxybenzofuran (7), egonol (8), homoegonol (9), salicifoliol (10), machicendonal (11), homoegonol glucoside (12), and 3β-acetoxyolean-12-en-28-aldehyde (13) were isolated from stem bark of Styrax obassia. Their chemical structures have been identified mainly by means of spectroscopic analysis. Their anti-inflammatory activity was evaluated against LPS-induced NO production in macrophage RAW264.7 cells.