Issue 1, 1982

Compounds with bridgehead nitrogen. Part 41. The reaction between trans-2-aminocycloalkanols and formaldehyde

Abstract

trans-2-Aminocyclopentanol and trans-2-aminocyclohexanol condense with formaldehyde to give single isomers of NN′-methanoperhydrocycloalkano[d,i][1,6,3,8]dioxadiazecines whereas trans-2-aminocycloheptanol and trans-2-aminocyclo-octanol give 1 : 1 mixtures of two isomeric bis(perhydrocycloaikeno-oxazol-3-yl)methanes. The formation of the two types of dimer is explained in terms of differences in ring fusion strain.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 2, 1982, 91-94

Compounds with bridgehead nitrogen. Part 41. The reaction between trans-2-aminocycloalkanols and formaldehyde

P. M. R. Barkworth and T. A. Crabb, J. Chem. Soc., Perkin Trans. 2, 1982, 91 DOI: 10.1039/P29820000091

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