Issue 10, 1995

Biocatalytic preparation of chiral alcohols by enantioselective reduction with immobilized cells of carrot

Abstract

The ability of immobilized cells of Daucus carota to reduce enantioselectively organic foreign substrates has been examined. The immobilized plant cells reduced, with excellent enantioselectivity, prochiral ketone substrates such as keto esters, aromatic ketones and heterocyclic aromatic ketones, leading to the corresponding chiral secondary alcohols with an enantiomeric purity of 52–99% ee in a chemical yield of 30–63%.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1995, 1295-1298

Biocatalytic preparation of chiral alcohols by enantioselective reduction with immobilized cells of carrot

Y. Akakabe, M. Takahashi, M. Kamezawa, K. Kikuchi, H. Tachibana, T. Ohtani and Y. Naoshima, J. Chem. Soc., Perkin Trans. 1, 1995, 1295 DOI: 10.1039/P19950001295

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