Issue 0, 1985

Necic acid synthons. Part 5. Total synthesis of (±)-retronecic acid and related compounds via zinc-mediated coupling of halogeno-esters

Abstract

Zinc-mediated coupling of suitably substituted halogeno esters affords access to (±)-retronecic acid (2) and related intermediates. These approaches lead to racemic retronecic acid on the one hand and to a diastereoisomeric mixture of the acid on the other.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1985, 2713-2717

Necic acid synthons. Part 5. Total synthesis of (±)-retronecic acid and related compounds via zinc-mediated coupling of halogeno-esters

F. Ameer, S. E. Drewes, R. Hoole, P. T. Kaye and A. T. Pitchford, J. Chem. Soc., Perkin Trans. 1, 1985, 2713 DOI: 10.1039/P19850002713

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