Issue 0, 1985

N-alkylation of some secondary styryl enamides

Abstract

The preparation of some secondary styryl enamides of both the Z- and E-configuration, and their exclusively N-alkylation through their anions is described. Partial configurational inversion is observed under certain conditions during the alkylation of the diastereoisomeric N-(2-phenyl-1-methylethenyl)ethanamides. Two further examples of the photoequilibration of a secondary enamide, and the preparation and N-benzylation of N-(2,2-diphenylethenyl)toluene-p-sulphonamide are also described.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1985, 831-836

N-alkylation of some secondary styryl enamides

R. Brettle, S. M. Shibib and K. J. Wheeler, J. Chem. Soc., Perkin Trans. 1, 1985, 831 DOI: 10.1039/P19850000831

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