Issue 0, 1982
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Studies on v-triazoles. Part 4. The 4-methoxybenzyl group, a versatile N-protecting group for the synthesis of N-unsubstituted v-triazoles

Derek R. Buckle  and  (Mrs.)Caroline J. M. Rockell  

Abstract

A series of readily prepared monocyclic N-(4-methoxybenzyl)-v-triazoles (1) have been converted into their N-unsubstituted derivatives (2) by treatment with trifluoroacetic acid at 65 °C. The procedure allows the synthesis of a range of N-unsubstituted v-triazoles. Its applicability to multicyclic systems is demonstrated by the synthesis of 3,9-dihydro-9-oxobenzopyrano[2,3-d]-v-triazole (5b), one of a series of compounds of interest as potential antiallergic agents.

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Article information

DOI
https://doi.org/10.1039/P19820000627
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1982, 627-630

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Studies on v-triazoles. Part 4. The 4-methoxybenzyl group, a versatile N-protecting group for the synthesis of N-unsubstituted v-triazoles

D. R. Buckle and C. J. M. Rockell, J. Chem. Soc., Perkin Trans. 1, 1982, 627 DOI: 10.1039/P19820000627

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