Issue 0, 1972
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Equilibration of 24,25-dibromides of lanosterol and derivatives

D. H. R. Barton,   H. MacGrillen,   P. D. Magnus,   C. H. Carlisle  and  P. A. Timmins  

Abstract

Bromination of lanosteryl acetate under conditions of kinetic control gives two 24,25-dibromides. A and B, in equal amounts. Thermodynamically controlled equilibration of these dibromides results in a 5:1 mixture of the two. The driving force is considered to be interaction between the 20-methyl group and the 24-bromine atom in the 24R-configuration. Configurations have been assigned to the dibromides from the results of an X-ray crystal structure determination on dibromide A.

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Article information

DOI
https://doi.org/10.1039/P19720001584
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1972, 1584-1587

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Equilibration of 24,25-dibromides of lanosterol and derivatives

D. H. R. Barton, H. MacGrillen, P. D. Magnus, C. H. Carlisle and P. A. Timmins, J. Chem. Soc., Perkin Trans. 1, 1972, 1584 DOI: 10.1039/P19720001584

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