Issue 6, 1987

Studies of metalloprotein species by directly coupled high-performance liquid chromatography inductively coupled plasma mass spectrometry

Abstract

High-performance liquid chromatography (HPLC) has been directly coupled to inductively coupled plasma mass spectrometry (ICP-MS) for trace metal speciation studies. The characteristics of HPLC-ICP-MS couplings have been investigated using the number of theoretical plates, peak tailing, rise time and wash-out time as criteria of merit. A short aerosol connection line was found to be optimal. In comparison with an in-line UV monitor, ICP-MS was found to give a comparable number of theoretical plates.

Article information

Article type
Paper

J. Anal. At. Spectrom., 1987,2, 607-610

Studies of metalloprotein species by directly coupled high-performance liquid chromatography inductively coupled plasma mass spectrometry

J. R. Dean, S. Munro, L. Ebdon, H. M. Crews and R. C. Massey, J. Anal. At. Spectrom., 1987, 2, 607 DOI: 10.1039/JA9870200607

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