Synthesis of acridones via Ir(iii)-catalyzed amination annulation of oxazoles with anthranils†
Lin
Dong 
*a
*a
Abstract
An unprecedented Ir(III)-catalyzed C–H activation/amination/annulation of 2-phenyloxazoles with anthranils for the highly selective preparation of acridone derivatives in one-pot under controlled conditions is reported. This protocol is characterized by atom economy and high regioselectivity. A wide range of anthranils with 2-phenyloxazoles were well tolerated and afforded the desired products in moderate to good yields, in which the anthranil serves as a convenient amination reagent.
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