Issue 5, 2024
From the journal:

RSC Advances

Update on novel synthetic approaches towards the construction of carbazole nuclei: a review

Saba Munawar,a   Ameer Fawad Zahoor, ORCID logo *a   Asim Mansha,a   Tanveer Hussain Bokharia  and  Ahmad Irfanb  

* Corresponding authors

a Department of Chemistry, Government College University Faisalabad, 38000-Faisalabad, Pakistan
E-mail: fawad.zahoor@gcuf.edu.pk

b Department of Chemistry, King Khalid University, Abha 61413, Saudi Arabia

Abstract

The carbazole scaffold is a significant entity in organic compounds due to its variety of biological and synthetic applications. Traditionally, carbazole skeletons have been synthesized either via the Grabe–Ullman method, Clemo–Perkin method or Tauber method. With the passage of time, these methods have been modified and explored to accomplish the synthesis of target compounds. These methods include hydroarylations, C–H activations, annulations and cyclization reactions mediated by a variety of catalysts to construct carbazole-based compounds. This brief review article intends to provide recent updates on important methodological developments reported for the synthesis of carbazole nuclei covering 2019–2023.

Graphical abstract: Update on novel synthetic approaches towards the construction of carbazole nuclei: a review

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Article information

DOI
https://doi.org/10.1039/D3RA07270C
Article type
Review Article
Submitted
25 Oct 2023
Accepted
10 Jan 2024
First published
18 Jan 2024
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2024,14, 2929-2946

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Update on novel synthetic approaches towards the construction of carbazole nuclei: a review

S. Munawar, A. F. Zahoor, A. Mansha, T. H. Bokhari and A. Irfan, RSC Adv., 2024, 14, 2929 DOI: 10.1039/D3RA07270C

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