Issue 40, 2023

InCl3-catalyzed intramolecular carbonyl–olefin metathesis

Abstract

An efficient and novel synthetic strategy for the generation of different carbocyclic moieties by ring closing carbonyl–olefin metathesis is reported. Herein, we describe a sustainably attractive protocol for one of the most powerful carbon–carbon bond-forming reactions, based on solvent-reduction, use of InCl3 catalyst, and microwave irradiation, affording target compounds with yields up to 96%.

Graphical abstract: InCl3-catalyzed intramolecular carbonyl–olefin metathesis

Supplementary files

Article information

Article type
Paper
Submitted
24 Jul 2023
Accepted
05 Sep 2023
First published
25 Sep 2023

Org. Biomol. Chem., 2023,21, 8141-8151

InCl3-catalyzed intramolecular carbonyl–olefin metathesis

M. G. Pizzio, Z. B. Cenizo, L. Méndez, A. M. Sarotti and E. G. Mata, Org. Biomol. Chem., 2023, 21, 8141 DOI: 10.1039/D3OB01170D

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