Issue 29, 2023

An activatable endoplasmic reticulum-targeted probe for NIR imaging-guided photothermal therapy

Abstract

An H2O2-activated, endoplasmic reticulum-targeted theranostic probe was developed. This designed probe could be activated by H2O2, resulting in increased NIR fluorescence and photothermal signals, thus achieving specific recognition of H2O2 and further photothermal therapy in the endoplasmic reticulum of H2O2-overexpressing cancer cells.

Graphical abstract: An activatable endoplasmic reticulum-targeted probe for NIR imaging-guided photothermal therapy

Supplementary files

Article information

Article type
Communication
Submitted
19 May 2023
Accepted
16 Jun 2023
First published
08 Jul 2023

Org. Biomol. Chem., 2023,21, 5919-5923

An activatable endoplasmic reticulum-targeted probe for NIR imaging-guided photothermal therapy

R. Chen, R. Wang, J. Sun, X. Dong, C. Dong, L. Sun, X. Gu and C. Zhao, Org. Biomol. Chem., 2023, 21, 5919 DOI: 10.1039/D3OB00782K

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