Issue 33, 2024

A ratiometric upconversion nanoprobe enables super-resolution imaging sensing of biothiols in living cells

Abstract

We have developed an upconversion luminescent ratiometric nanoprobe, specifically designed for detection of biothiols with high sensitivity (∼25 nM) at the single-particle level. Using a single-particle localization and rendering method, this nanoprobe enables super-resolution imaging sensing of biothiols within a confined 22 nm space in living cells.

Graphical abstract: A ratiometric upconversion nanoprobe enables super-resolution imaging sensing of biothiols in living cells

Supplementary files

Article information

Article type
Communication
Submitted
24 Dec 2023
Accepted
23 Mar 2024
First published
25 Mar 2024

Chem. Commun., 2024,60, 4447-4450

A ratiometric upconversion nanoprobe enables super-resolution imaging sensing of biothiols in living cells

H. Chen, R. Wang, J. Cheng, L. Wang and H. He, Chem. Commun., 2024, 60, 4447 DOI: 10.1039/D3CC06242B

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