Issue 36, 2022
From the journal:

Organic & Biomolecular Chemistry

Meyer–Schuster rearrangement of propargylic alcohols mediated by phosphorus-containing Brønsted acid catalysts†

Lalita Radtanajiravong, ORCID logo a   Jake Peters,a   Jake Hummella  and  Silvia Díez-González ORCID logo *a  

* Corresponding authors

a Imperial College London, Department of Chemistry, MSRH, 82 Wood Lane, London W12 0BZ, UK
E-mail: s.diez-gonzalez@imperial.ac.uk

Abstract

Commercially available (aqueous) hypophosphorus acid is an efficient catalyst for the synthesis of α,β-unsaturated carbonyl compounds from their corresponding propargylic alcohols. Reactions were carried out in technical toluene in the presence of air and in several instances the desired products were isolated analytically pure after a simple work-up.

Graphical abstract: Meyer–Schuster rearrangement of propargylic alcohols mediated by phosphorus-containing Brønsted acid catalysts

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Article information

DOI
https://doi.org/10.1039/D2OB01259F
Article type
Paper
Submitted
14 Jul 2022
Accepted
31 Aug 2022
First published
31 Aug 2022
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2022,20, 7338-7342

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Meyer–Schuster rearrangement of propargylic alcohols mediated by phosphorus-containing Brønsted acid catalysts

L. Radtanajiravong, J. Peters, J. Hummell and S. Díez-González, Org. Biomol. Chem., 2022, 20, 7338 DOI: 10.1039/D2OB01259F

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