Issue 17, 2022
From the journal:

New Journal of Chemistry

A turn-on fluorescent probe based on indolizine for the detection of sulfite†

Renle Cui,a   Yunlong Gao,b   Haiyan Ge,a   Guowei Shi,a   Yongchao Li,a   Hao Liu,a   Chuanjun Ma,a   Yanqing Ge ORCID logo *a  and  Caihong Liu*a  

* Corresponding authors

a Department of Chemistry and Pharmaceutical Engineering, Shandong First Medical University, Shandong Academy of Medical Sciences, Taian, Shandong 271016, P. R. China
E-mail: geyanqing2016@126.com, liuch7688@163.com

b Center for disease control and prevention, Weifang binhai economic and technological development zone, Weifang, Shandong, P. R. China

Abstract

Numerous SO32−/HSO3− fluorescent probes have been reported based on various mechanisms. However, most probes are constructed from classic dyes such as coumarin, BODIPY, and cyanine. The development of a new fluorophore with excellent performance is still required. CRL-1, a turn-on fluorescent probe based on indolizines, was developed for the detection of sulfite. Compared with other analytes, probe CRL-1 showed a short response time (within 10 s) and excellent selectivity and had strong fluorescence emission at 458 nm. The probe's LOD was 8.1 μM. Furthermore, cell imaging experiments suggested that the probe can be useful in biological systems.

Graphical abstract: A turn-on fluorescent probe based on indolizine for the detection of sulfite

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Supplementary files

Article information

DOI
https://doi.org/10.1039/D2NJ00238H
Article type
Paper
Submitted
15 Jan 2022
Accepted
15 Mar 2022
First published
31 Mar 2022

New J. Chem., 2022,46, 8088-8093

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A turn-on fluorescent probe based on indolizine for the detection of sulfite

R. Cui, Y. Gao, H. Ge, G. Shi, Y. Li, H. Liu, C. Ma, Y. Ge and C. Liu, New J. Chem., 2022, 46, 8088 DOI: 10.1039/D2NJ00238H

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