Issue 5, 2022
From the journal:

Soft Matter

Impact of cationic surfactant-induced DNA compaction on the characteristics of a minor groove bound flavonol†

Dipanjan Halder ORCID logo a  and  Pradipta Purkayastha ORCID logo *a  

* Corresponding authors

a Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur 741246, WB, India
E-mail: ppurkayastha@iiserkol.ac.in

Abstract

3-Hydroxyflavone (3-HF), which binds to the minor groove of DNA, is a strong antioxidant and hence a potent therapeutic and diagnostic agent. A special photo-property, called excited state intramolecular proton transfer (ESIPT), makes the 3-HF derivatives sensitive to the cellular hydrophobic microenvironment. The present study depicts the various changes in the ESIPT of 3-HF due to cationic surfactant-induced compaction of DNA.

Graphical abstract: Impact of cationic surfactant-induced DNA compaction on the characteristics of a minor groove bound flavonol

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Article information

DOI
https://doi.org/10.1039/D1SM01792F
Article type
Communication
Submitted
21 Dec 2021
Accepted
08 Jan 2022
First published
10 Jan 2022

Soft Matter, 2022,18, 938-942

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Impact of cationic surfactant-induced DNA compaction on the characteristics of a minor groove bound flavonol

D. Halder and P. Purkayastha, Soft Matter, 2022, 18, 938 DOI: 10.1039/D1SM01792F

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