Issue 7, 2021
From the journal:

Organic Chemistry Frontiers

Rhodium-catalyzed enone carbonyl directed C–H activation for the synthesis of indanones containing all-carbon quaternary centers†

Jiang Lou, ORCID logo ‡ab   Wenjia Han, ORCID logo ‡ab   Zhuqing Liu ORCID logo *bc  and  Jiaqi Xiao*bc  

* Corresponding authors

a Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, P. R. China

b State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, P. R. China
E-mail: liuzhuqing@qlu.edu.cn, jiaqixiao@qlu.edu.cn

c Advanced Research Institute for Multidisciplinary Science, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, P. R. China

Abstract

Rh(III)-Catalyzed enone carbonyl directed annulative coupling of α-aroyl ketene dithioacetals and diazo compounds has been realized via aryl and olefinic C–H bond activation. This transformation offers highly functionalized indanone derivatives bearing a quaternary carbon stereocenter at the β-position. The protocol exhibits high efficiency, broad substrate scope, and high compatibility with functional groups.

Graphical abstract: Rhodium-catalyzed enone carbonyl directed C–H activation for the synthesis of indanones containing all-carbon quaternary centers

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D1QO00056J
Article type
Research Article
Submitted
12 Jan 2021
Accepted
03 Feb 2021
First published
05 Feb 2021

Org. Chem. Front., 2021,8, 1447-1453

Permissions

Request permissions

Rhodium-catalyzed enone carbonyl directed C–H activation for the synthesis of indanones containing all-carbon quaternary centers

J. Lou, W. Han, Z. Liu and J. Xiao, Org. Chem. Front., 2021, 8, 1447 DOI: 10.1039/D1QO00056J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements