Issue 33, 2021

Electrooxidative double C–H/C–H coupling of phenols with 3-phenylbenzothiophenes: facile access to benzothiophene derivatives

Abstract

An efficient electrooxidative double C–H/C–H coupling of phenols with 3-phenylbenzothiophene has been developed under external oxidant- and catalyst-free conditions. This strategy could enable the highly tunable access to benzothiophene derivatives and exhibited broad substrate generality under mild conditions. The reaction is likely to proceed via the cross-coupling of the p-methoxylphenol radical and the 3-phenylbenzothiophene radical cation.

Graphical abstract: Electrooxidative double C–H/C–H coupling of phenols with 3-phenylbenzothiophenes: facile access to benzothiophene derivatives

Supplementary files

Article information

Article type
Communication
Submitted
23 Jun 2021
Accepted
02 Aug 2021
First published
03 Aug 2021

Org. Biomol. Chem., 2021,19, 7156-7160

Electrooxidative double C–H/C–H coupling of phenols with 3-phenylbenzothiophenes: facile access to benzothiophene derivatives

Y. Yue, J. Chao, Z. Wang, Y. Yang, Y. Ye, C. Sun, X. Guo and J. Liu, Org. Biomol. Chem., 2021, 19, 7156 DOI: 10.1039/D1OB01208H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements