Issue 5, 2022
From the journal:

New Journal of Chemistry

Preparation of antibacterial nanofibers by electrospinning polyvinyl alcohol containing a luteolin hydroxypropyl-β-cyclodextrin inclusion complex†

Xiaoyan Wang,a   Xiaona Hu,a   Shiqing Li,a   Wenhui Shi,a   Shujing Li ORCID logo *ab  and  Yuxi Zhang*c  

* Corresponding authors

a College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, P. R. China
E-mail: lishujing@th.btbu.edu.cn

b Beijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University, Beijing, P. R. China

c Technical Institute of Physics and Chemistry, Chinese Academy of Science, Beijing, P. R. China
E-mail: zhangyuxi@mail.ipc.ac.cn

Abstract

Sustained-release antimicrobial nanofibers (PVA-Lut-IC-NF) were prepared by incorporating a luteolin-hydroxypropyl-β-cyclodextrin inclusion complex (Lut-IC) into polyvinyl alcohol (PVA) via the electrospinning technique. PVA-Lut-IC-NF exhibits excellent water solubility and thermal stability. The results also showed significant antibacterial effects of PVA-Lut-IC-NF against Staphylococcus aureus, Candida albicans and Escherichia coli. Moreover, because of the sensitivities of different cytoderms to Lut, PVA-Lut-IC-NF was more effective against Staphylococcus aureus than Candida albicans and Escherichia coli. Additionally, PVA-Lut-IC-NF showed an appropriate slow release and maintained effective concentration in vitro release. PVA-Lut-IC-NF could have potential applications in food, pharmaceuticals, and healthcare due to its efficient antibacterial activity along with enhanced water solubility and thermal stability.

Graphical abstract: Preparation of antibacterial nanofibers by electrospinning polyvinyl alcohol containing a luteolin hydroxypropyl-β-cyclodextrin inclusion complex

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Article information

DOI
https://doi.org/10.1039/D1NJ04922D
Article type
Paper
Submitted
15 Oct 2021
Accepted
24 Dec 2021
First published
27 Dec 2021

New J. Chem., 2022,46, 2360-2367

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Preparation of antibacterial nanofibers by electrospinning polyvinyl alcohol containing a luteolin hydroxypropyl-β-cyclodextrin inclusion complex

X. Wang, X. Hu, S. Li, W. Shi, S. Li and Y. Zhang, New J. Chem., 2022, 46, 2360 DOI: 10.1039/D1NJ04922D

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