SCHEDULED MAINTENANCE
Progress in recent development of stereoselective synthesis of β2-amino acid derivatives from β-nitroacrylate derivatives
Abstract
The synthesis and properties of β-amino acids have drawn considerable attention owing to their ubiquitous presence in naturally occurring products of biological importance. While β3-amino acids can be readily prepared from α-amino acids via one-carbon homologation, the synthesis of β2-amino acids generally requires multistep efforts. This review focuses on the recent advances in the synthesis of β2-amino acids and their derivatives from substituted β-nitropropionate analogues obtained from the stereoselective transformation of β-nitroacrylates.
- This article is part of the themed collection: Synthetic methodology in OBC
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