Issue 48, 2018, Issue in Progress
From the journal:

RSC Advances

Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

Chengwan Xia,†a   Diya Xie,†a   Lang Xiong,a   Qian Zhang,a   Yang Wang,a   Zezheng Wang,a   Yuxin Wang,*a   Bin Li ORCID logo *a  and  Chao Zhang*ab  

* Corresponding authors

a Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210093, P. R. China
E-mail: 904489973@qq.com, 1libin@163.com, 1446980166@qq.com

b Collaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China

Abstract

Herein, we reported nitroxide radical-modified CuS nanoparticles (CuS–NO˙ NPs), and they exhibited a typical absorption peak at 1182 nm. Due to such a long wavelength absorbance, CuS–NO˙ NPs exhibited excellent therapeutic outcome and low damage to normal tissues. Besides, we simultaneously achieved CuS–NO˙ NPs for MRI and CT dual-modal imaging, which successfully provided a new strategy for imaging-guided tumor treatment, thus increasing potential clinical applications for cancer treatment.

Graphical abstract: Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

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Article information

DOI
https://doi.org/10.1039/C8RA04501A
Article type
Paper
Submitted
26 May 2018
Accepted
14 Jul 2018
First published
31 Jul 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 27382-27389

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Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

C. Xia, D. Xie, L. Xiong, Q. Zhang, Y. Wang, Z. Wang, Y. Wang, B. Li and C. Zhang, RSC Adv., 2018, 8, 27382 DOI: 10.1039/C8RA04501A

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