Issue 34, 2018

Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

Abstract

Encapsulation of ionic nanoparticles in a hydrogel microparticle, i.e. microgel, produces a target-stimulated probe for molecular detection. Selective reactive oxygen species (ROS) release the enclosed cations from the microgel which subsequently turn on the fluorogenic dyes to emit intense fluorescence, permitting rapid detection of ROS or ROS-producing molecules. The ROS-responsive microgel provides the advantages of simple fabrication, bright and stable signals, easy handling, and rapid response, carrying great promise in biomedical applications.

Graphical abstract: Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

Supplementary files

Article information

Article type
Communication
Submitted
21 Feb 2018
Accepted
27 Mar 2018
First published
28 Mar 2018

Chem. Commun., 2018,54, 4329-4332

Author version available

Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

Y. Liu, Y. Wang, S. Sedano, Q. Jiang, Y. Duan, W. Shen, J. Jiang and W. Zhong, Chem. Commun., 2018, 54, 4329 DOI: 10.1039/C8CC01432A

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