Issue 78, 2017

A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues

Abstract

A fluorescent probe that enables ratiometric imaging of endogenous hypochlorous acid (HOCl) in cells and tissues by two-photon microscopy is developed based on a red-emitting acetyl-benzocoumarin (AcBC) dye. An oxathiolane group in the probe reacts with HOCl to generate the AcBC dye, which involves a ratiometric fluorescence change only toward HOCl along with high sensitivity.

Graphical abstract: A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues

Supplementary files

Article information

Article type
Communication
Submitted
26 Jul 2017
Accepted
06 Sep 2017
First published
06 Sep 2017

Chem. Commun., 2017,53, 10800-10803

A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues

Y. W. Jun, S. Sarkar, S. Singha, Y. J. Reo, H. R. Kim, J. Kim, Y. Chang and K. H. Ahn, Chem. Commun., 2017, 53, 10800 DOI: 10.1039/C7CC05834A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements