Issue 58, 2015

Detection of telomerase on upconversion nanoparticle modified cellulose paper

Abstract

Herein we report a convenient and sensitive method for the detection of telomerase activity based on upconversion nanoparticle (UCNP) modified cellulose paper. Compared with many solution-phase systems, this paper chip is more stable and easily stores the test results. What's more, the low background fluorescence of the UCNPs increases the sensitivity of this method, and the low telomerase levels in different cell lines can clearly be discriminated by the naked eye.

Graphical abstract: Detection of telomerase on upconversion nanoparticle modified cellulose paper

Supplementary files

Article information

Article type
Communication
Submitted
11 May 2015
Accepted
10 Jun 2015
First published
10 Jun 2015

Chem. Commun., 2015,51, 11630-11633

Detection of telomerase on upconversion nanoparticle modified cellulose paper

F. Wang, W. Li, J. Wang, J. Ren and X. Qu, Chem. Commun., 2015, 51, 11630 DOI: 10.1039/C5CC03902A

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