Issue 60, 2015
From the journal:

Chemical Communications

Palladium-catalysed decarboxylative nitrile insertion via C–H activation or self-coupling of indole-2-carboxylic acids: a new route to indolocarbolines and triindoles†

R. N. Prasad Tulichalaa  and  K. C. Kumara Swamy*a  

* Corresponding authors

a School of Chemistry, University of Hyderabad, Hyderabad 500 046, Telangana, India
E-mail: kckssc@uohyd.ac.in, kckssc@yahoo.com
Fax: +91-40-23012460
Tel: +91-40-231348560

Abstract

Palladium catalysed-reaction of indole carboxylic acids with nitriles in the presence of Ag2CO3 proceeds via decarboxylative dual C–H activation leading to the nitrile insertion products, triazaindeno-fluorenes (indolocarbolines); in the absence of nitrile, diindolocarbazoles (heptacyclic triindoles or triazatruxenes) are formed.

Graphical abstract: Palladium-catalysed decarboxylative nitrile insertion via C–H activation or self-coupling of indole-2-carboxylic acids: a new route to indolocarbolines and triindoles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5CC03160E
Article type
Communication
Submitted
16 Apr 2015
Accepted
16 Jun 2015
First published
16 Jun 2015

Chem. Commun., 2015,51, 12008-12011

Author version available

Download author version (PDF)

Permissions

Request permissions

Palladium-catalysed decarboxylative nitrile insertion via C–H activation or self-coupling of indole-2-carboxylic acids: a new route to indolocarbolines and triindoles

R. N. Prasad Tulichala and K. C. Kumara Swamy, Chem. Commun., 2015, 51, 12008 DOI: 10.1039/C5CC03160E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements