Bi(OTf)3-catalyzed three-component synthesis of α-amino acid derivatives

Angelika E. Schneider; Tamara Beisel; Andrej Shemet; Georg Manolikakes

doi:10.1039/C4OB00265B

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Bi(OTf)₃-catalyzed three-component synthesis of α-amino acid derivatives†

Angelika E. Schneider,^a Tamara Beisel,^a Andrej Shemet^a and Georg Manolikakes*^a

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* Corresponding authors

^a Department of Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany
E-mail: g.manolikakes@chemie.uni-frankfurt.de

Abstract

A highly efficient Bi(OTf)₃-catalyzed multicomponent synthesis of arylglycines from readily available starting materials is described. The reaction proceeds under mild conditions and provides a general route to various N-protected arylglycines.

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Article information

DOI: https://doi.org/10.1039/C4OB00265B
Article type: Communication
Submitted: 05 Feb 2014
Accepted: 18 Feb 2014
First published: 18 Feb 2014
This article is Open Access

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Org. Biomol. Chem., 2014,12, 2356-2359

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Bi(OTf)₃-catalyzed three-component synthesis of α-amino acid derivatives

A. E. Schneider, T. Beisel, A. Shemet and G. Manolikakes, Org. Biomol. Chem., 2014, 12, 2356 DOI: 10.1039/C4OB00265B

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Organic & Biomolecular Chemistry