Issue 67, 2014
From the journal:

Chemical Communications

Ultrafast colorimetric detection of nucleic acids based on the inhibition of the oxidase activity of cerium oxide nanoparticles†

Moon Il Kim,ab   Ki Soo Parka  and  Hyun Gyu Park*a  

* Corresponding authors

a Department of Chemical and Biomolecular Engineering (BK 21+ program), KAIST, Daejeon 305-701, Republic of Korea
E-mail: hgpark@kaist.ac.kr
Fax: +82-42-350-3910
Tel: +82-42-350-3932

b Department of BioNano Technology, Gachon University, Gyeonggi-do 461-701, Republic of Korea

Abstract

A label-free colorimetric method to detect nucleic acids, which relies on target DNA induced shielding of the oxidase activity of CeO2 NPs, is developed. With this novel strategy, target nucleic acids can be identified within a few minutes and without the need for post-purification of PCR products.

Graphical abstract: Ultrafast colorimetric detection of nucleic acids based on the inhibition of the oxidase activity of cerium oxide nanoparticles

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Article information

DOI
https://doi.org/10.1039/C4CC03841J
Article type
Communication
Submitted
20 May 2014
Accepted
06 Jul 2014
First published
07 Jul 2014

Chem. Commun., 2014,50, 9577-9580

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Ultrafast colorimetric detection of nucleic acids based on the inhibition of the oxidase activity of cerium oxide nanoparticles

M. I. Kim, K. S. Park and H. G. Park, Chem. Commun., 2014, 50, 9577 DOI: 10.1039/C4CC03841J

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