Issue 39, 2011

Gold/copper-catalyzed activation of the aci-form of nitromethane in the synthesis of methylene-bridged bis-1,3-dicarbonyl compounds

Abstract

Activation of the aci-form of nitromethane using Lewis acids for the attack of carbon nucleophiles was studied. 1,3-Dicarbonyl compounds in the presence of catalytic amounts of AuCl3 or Cu(OTf)2 in nitromethane solvent could be converted into methylene-bridged bis-1,3-dicarbonyl compounds.

Graphical abstract: Gold/copper-catalyzed activation of the aci-form of nitromethane in the synthesis of methylene-bridged bis-1,3-dicarbonyl compounds

Supplementary files

Article information

Article type
Communication
Submitted
09 Aug 2011
Accepted
22 Aug 2011
First published
06 Sep 2011

Chem. Commun., 2011,47, 11143-11145

Gold/copper-catalyzed activation of the aci-form of nitromethane in the synthesis of methylene-bridged bis-1,3-dicarbonyl compounds

R. Balamurugan and S. Manojveer, Chem. Commun., 2011, 47, 11143 DOI: 10.1039/C1CC14926A

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