Abstract
The fluorescence spectrum of the homopolymeric double helix poly(dG)·poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC)·poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.
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Electronic supplementary information (ESI) available: Synthesis and characterization of poly(dG)·poly(dC); details of spectroscopic measurements and fits of the fluorescence decays.
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Vayá, I., Changenet-Barret, P., Gustavsson, T. et al. Long-lived fluorescence of homopolymeric guanine—cytosine DNA duplexes. Photochem Photobiol Sci 9, 1193–1195 (2010). https://doi.org/10.1039/c0pp00201a
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DOI: https://doi.org/10.1039/c0pp00201a