Issue 4, 2011
From the journal:

Analytical Methods

Peptidome workflow of serum and urine samples for biomarker discovery

Yao Gao,a   Lin Lin,a   Zhenzhen Huang,a   Yongjing Chena  and  Wei Hang*a  

* Corresponding authors

a Department of Chemistry, Key Laboratory of Analytical Sciences, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China
E-mail: weihang@xmu.edu.cn
Fax: +86 592 2184618
Tel: +86 592 2184618

Abstract

Peptidomics plays an important role in clinical proteomics and disease-associated biomarker discovery. It has exhibited mounting potential in early noninvasive diagnosis, prognosis, and treatment evaluation of diseases. This article presents an introduction of peptidomics, the entire peptidomic workflows for serum and urine samples, and a brief overview of recent works in this area. The review is designed to enable researchers to find the most suited strategy for their peptidome studies.

Graphical abstract: Peptidome workflow of serum and urine samples for biomarker discovery

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Article information

DOI
https://doi.org/10.1039/C0AY00705F
Article type
Minireview
Submitted
20 Nov 2010
Accepted
22 Jan 2011
First published
17 Feb 2011

Anal. Methods, 2011,3, 773-779

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Peptidome workflow of serum and urine samples for biomarker discovery

Y. Gao, L. Lin, Z. Huang, Y. Chen and W. Hang, Anal. Methods, 2011, 3, 773 DOI: 10.1039/C0AY00705F

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