Issue 18, 2010
From the journal:

Chemical Communications

Comparing biomimetic and biological receptors for insulin sensing†

Romana Schirhagl,a   Dagmar Podlipna,a   Peter A. Lieberzeita  and  Franz L. Dickert*a  

* Corresponding authors

a University of Vienna, Department of Analytical Chemistry, Währingerstrasse 38, Austria
E-mail: franz.dickert@univie.ac.at

Abstract

Biological information such as recognition abilities of antibodies can be transferred to man-made systems by imprinting. For instance, sensor layers with insulin-selective cavities yield similar selectivity and sensitivity as IgG. True “artificial antibodies” are achieved by synthesizing “polymer copies” retaining the original binding properties of anti-insulin IgG via two-step imprinting.

Graphical abstract: Comparing biomimetic and biological receptors for insulin sensing

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Article information

DOI
https://doi.org/10.1039/C000936A
Article type
Communication
Submitted
14 Jan 2010
Accepted
29 Mar 2010
First published
09 Apr 2010

Chem. Commun., 2010,46, 3128-3130

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Comparing biomimetic and biological receptors for insulin sensing

R. Schirhagl, D. Podlipna, P. A. Lieberzeit and F. L. Dickert, Chem. Commun., 2010, 46, 3128 DOI: 10.1039/C000936A

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