Issue 16, 2010
From the journal:

Chemical Communications

Copper(ii)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives†

Yingguang Zhu,a   Changwei Zhai,a   Liping Yanga  and  Wenhao Hu*a  

* Corresponding authors

a East China Normal University, 3663 Zhongshan Bei Road, Shanghai 200062, China
E-mail: whu@chem.ecnu.edu.cn

Abstract

Copper(II) complexes are efficient catalysts in three-component reactions of aryl diazoacetates with alcohols and chalcones to give γ-hydroxyketone derivatives in high yield with excellent diastereoselectivity. The resulting coupling adducts can be easily converted into furan-containing oligoaryls, tetrahydrofuran and 2,3-dihydrofuran derivatives.

Graphical abstract: Copper(ii)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives

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Article information

DOI
https://doi.org/10.1039/B924845E
Article type
Communication
Submitted
25 Nov 2009
Accepted
08 Feb 2010
First published
04 Mar 2010

Chem. Commun., 2010,46, 2865-2867

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Copper(II)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives

Y. Zhu, C. Zhai, L. Yang and W. Hu, Chem. Commun., 2010, 46, 2865 DOI: 10.1039/B924845E

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