Issue 1, 2008
From the journal:

Chemical Communications

A new role for cisplatin: probing ribosomal RNA structure

Keshab Rijala  and  Christine S. Chow*a  

* Corresponding authors

a Department of Chemistry, Wayne State University, Detroit, Michigan, USA
E-mail: csc@chem.wayne.edu
Fax: +01 313-577-8822
Tel: +01 313-577-2594

Abstract

In this study, cisplatin, the well-known anticancer drug, was used to probe accessible purine residues in E. coli16S ribosomal RNA (rRNA), free or in the context of 30S subunits or 70S ribosomes, both in vitro and in vivo.

Graphical abstract: A new role for cisplatin: probing ribosomal RNA structure

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Article information

DOI
https://doi.org/10.1039/B816633A
Article type
Communication
Submitted
23 Sep 2008
Accepted
17 Oct 2008
First published
10 Nov 2008

Chem. Commun., 2008

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A new role for cisplatin: probing ribosomal RNA structure

K. Rijal and C. S. Chow, Chem. Commun., 2008 DOI: 10.1039/B816633A

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