Issue 4, 2007

α-Amino acid Tröger base derivatives, possible conformationally restricted scaffolds?

Abstract

The first synthesis of innovative α-amino acid conjugates of Tröger base is reported; their potential application as conformationally restricted scaffolds is proposed and has been investigated using high level ab initio calculations.

Graphical abstract: α-Amino acid Tröger base derivatives, possible conformationally restricted scaffolds?

Supplementary files

Article information

Article type
Communication
Submitted
04 Oct 2006
Accepted
07 Dec 2006
First published
15 Dec 2006

Chem. Commun., 2007, 389-391

α-Amino acid Tröger base derivatives, possible conformationally restricted scaffolds?

S. P. Bew, L. Legentil, V. Scholier and S. V. Sharma, Chem. Commun., 2007, 389 DOI: 10.1039/B614371G

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