Issue 11, 2006
From the journal:

Soft Matter

Nanopatterning proteins and peptides

Karen L. Christman,ab   Vanessa D. Enriquez-Riosa  and  Heather D. Maynard*ab  

* Corresponding authors

a Department of Chemistry and Biochemistry, 607 Charles E. Young Drive East, Los Angles, CA 90095-1569

b California NanoSystems Institute, University of California Los Angeles, 6722 Boelter Hall, Los Angles, CA 90095-7151
E-mail: maynard@chem.ucla.edu.
Fax: 01 310 825 0767
Tel: 01 310 267 5162

Abstract

A variety of techniques have been developed to site-specifically immobilize biomolecules onto surfaces with resolutions below one micron. The ability to pattern proteins and peptides in particular has great potential for applications in biosensors, biomaterials, and tissue engineering. For example, immobilizing proteins at the nanoscale could lead to the development of diagnostic protein nanoarrays, while patterning peptides could lead to greater control over the cell/biomaterial interface. This review discusses the methods that have been reported for patterning proteins and peptides with submicron and nanometer resolutions.

Graphical abstract: Nanopatterning proteins and peptides

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Article information

DOI
https://doi.org/10.1039/B611000B
Article type
Review Article
Submitted
31 Jul 2006
Accepted
08 Sep 2006
First published
29 Sep 2006

Soft Matter, 2006,2, 928-939

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Nanopatterning proteins and peptides

K. L. Christman, V. D. Enriquez-Rios and H. D. Maynard, Soft Matter, 2006, 2, 928 DOI: 10.1039/B611000B

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