Issue 10, 2006

Glycoconjugates of gadolinium complexes for MRI applications

Abstract

Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.

Graphical abstract: Glycoconjugates of gadolinium complexes for MRI applications

Supplementary files

Article information

Article type
Communication
Submitted
19 Dec 2005
Accepted
25 Jan 2006
First published
08 Feb 2006

Chem. Commun., 2006, 1064-1066

Glycoconjugates of gadolinium complexes for MRI applications

D. A. Fulton, E. M. Elemento, S. Aime, L. Chaabane, M. Botta and D. Parker, Chem. Commun., 2006, 1064 DOI: 10.1039/B517997A

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