Issue 5, 1977
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Absolute configuration of 2,3-dihydroxy-3-methylpentanoic acid, an intermediate in the biosynthesis of isoleucine, and its identity with the esterifying acid of the pyrrolizidine alkaloid strigosine

David H. G. Crout  and  David Whitehouse  

Abstract

The (–)-erythro- and (–)-threo-isomers of 2,3-dihydroxy-3-methylpentanoicacid (I) have been synthesised. The (–)-erythro-isomer has been shown to have the absolute configuration 2R,3R and to be identical with the naturally occurring (–)-acid, a precursor of isoloucine (II), and with the esterifying acid of the pyrrolizidine alkaloid Strigosine.

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Article information

DOI
https://doi.org/10.1039/P19770000544
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1977, 544-549

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Absolute configuration of 2,3-dihydroxy-3-methylpentanoic acid, an intermediate in the biosynthesis of isoleucine, and its identity with the esterifying acid of the pyrrolizidine alkaloid strigosine

D. H. G. Crout and D. Whitehouse, J. Chem. Soc., Perkin Trans. 1, 1977, 544 DOI: 10.1039/P19770000544

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