Issue 3, 2020
From the journal:

Chemical Science

Dandelion flower-like micelles†

Yongchao Yao, ORCID logo ‡a   Deqiu Xu,‡bc   Yuhong Zhu,a   Xin Dai,a   Yunlong Yu,a   Jianbin Luo ORCID logo *b  and  Shiyong Zhang ORCID logo *a  

* Corresponding authors

a National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu 610064, China
E-mail: szhang@scu.edu.cn

b College of Chemistry and Environmental Protection Engineering, Southwest Minzu University, Chengdu 610041, China
E-mail: luojb1971@163.com

c Sichuan Guojian Inspection Co., Ltd., Luzhou, Sichuan, China

Abstract

Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s−1. Similar to the property of dandelion flowers dispersing their seeds over a long distance, the DFMs demonstrated enhanced multicellular tumor spheroid (MTS) penetration, a useful property in the treatment of many diseases including cancer, infection-of-biofilm diseases and ocular problems.

Graphical abstract: Dandelion flower-like micelles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9SC05741B
Article type
Edge Article
Submitted
13 Nov 2019
Accepted
23 Nov 2019
First published
03 Dec 2019
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY-NC license

Chem. Sci., 2020,11, 757-762

Permissions

Request permissions

Dandelion flower-like micelles

Y. Yao, D. Xu, Y. Zhu, X. Dai, Y. Yu, J. Luo and S. Zhang, Chem. Sci., 2020, 11, 757 DOI: 10.1039/C9SC05741B

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements