* Corresponding authors

^a Sue and Bill Gross Stem Cell Research Center, Sue & Bill Gross Hall CIRM Institute, University of California, Irvine, 845 Health Sciences Road, Suite 3027, Irvine, CA 92697, USA
E-mail: weianz@uci.edu
Tel: +949 824 9744

^b Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, CA 92697, USA

^c Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA 92697, USA

^d Edwards Life Sciences Center for Advanced Cardiovascular Technology, University of California, Irvine, Irvine, CA 92697, USA

^e Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA

^f Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA

^g Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA

^h Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China

ⁱ Suzhou Institute of Systems Medicine, Suzhou 215123, China

^j Amberstone Biosciences LLC, 23181 Verdugo, Suite 106, Laguna Hills, CA 92653, USA
E-mail: george@amberstonebio.com