SCHEDULED MAINTENANCE
Imine-functionalized thioether Zn(ii) turn-on fluorescent sensor and its selective sequential logic operations with H2PO4−, DFT computation and live cell imaging†
Abstract
The diformyl thioether Schiff base (H2L) exhibits fluorescent sensing behaviour towards Zn2+ with a limit of detection (LOD) of 0.050 μM, which is far below the WHO guideline (76 μM) in drinking water. The formation of a 1 : 1 metal-to-ligand complex, [ZnL], has been ascertained by X-ray crystallography, Job's plot and mass spectra. The fluorogenic complex, [ZnL] (either in situ or a solution of the isolated complex) has shown selective ON–OFF emission toward H2PO4−. A two-input, one-output sequential INHIBIT logic circuit has been constructed from H2L, Zn2+ and H2PO4−. The practical applicability of H2L has been examined by the identification of Zn2+ and H2PO4− in the intracellular fluid of African monkey Vero cells.
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