Issue 27, 2016

Nonenzymatic electrochemical detection of rutin on Pt nanoparticles/graphene nanocomposite modified glassy carbon electrode

Abstract

In this article, a nonenzymatic electrochemical sensor based on chemically reduced graphene oxide (RGO) and a Pt nanoparticles (PtNPs) modified glassy carbon electrode has been fabricated and used to determine rutin. The nanocomposites of PtNPs/RGO were characterized by transmission electron microscopy and X-ray diffraction, and the electrochemical behaviors of rutin on PtNPs/RGO were demonstrated by cyclic voltammetry and differential pulse voltammetry. The as-fabricated electrochemical sensor for rutin exhibited a wide linear range from 0.057 to 102.59 μM with a detection limit of 0.02 μM (S/N = 3). Additionally, the as-prepared electrode displayed a good reproducibility, stability and anti-interference ability for the detection of rutin. Finally, the electrode was successfully applied for the determination of rutin in pharmaceutical tablets.

Graphical abstract: Nonenzymatic electrochemical detection of rutin on Pt nanoparticles/graphene nanocomposite modified glassy carbon electrode

Article information

Article type
Paper
Submitted
10 May 2016
Accepted
04 Jun 2016
First published
06 Jun 2016

Anal. Methods, 2016,8, 5435-5440

Nonenzymatic electrochemical detection of rutin on Pt nanoparticles/graphene nanocomposite modified glassy carbon electrode

S. Li, B. Yang, J. Wang, D. Bin, C. Wang, K. Zhang and Y. Du, Anal. Methods, 2016, 8, 5435 DOI: 10.1039/C6AY01348A

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