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Photochemical synthesis of biocompatible and antibacterial silver nanoparticles embedded within polyurethane polymers

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Abstract

In situ light initiated synthesis of silver nanoparticles (AgNP) was employed for AgNP incorporation within the polymeric matrices of medical grade polyurethane. The resulting materials showed improved antibacterial and antibiofilm activity against Pseudomonas aeruginosa with negligible toxicity for human primary skin cells and erythrocytes.

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Authors and Affiliations

  1. Department of Chemistry and Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, Ontario, K1N 6N5, Canada

    Sara Saez, Chiara Fasciani, Kevin G. Stamplecoskie, M. Luisa Marin & Juan C. Scaiano

  2. Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

    Luke Brian-Patrick Gagnon & Thien-Fah Mah

  3. Instituto Universitario Mixto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Avenida de los Naranjos s/n, 46022, Valencia, Spain

    M. Luisa Marin

  4. Bio-Nanomaterials Chemistry and Engineering Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, 40 Ruskin street, Ottawa, Ontario, K1Y 4W7, Canada

    Emilio I. Alarcon

Authors
  1. Sara Saez
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  2. Chiara Fasciani
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  3. Kevin G. Stamplecoskie
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  4. Luke Brian-Patrick Gagnon
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  5. Thien-Fah Mah
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  6. M. Luisa Marin
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  7. Emilio I. Alarcon
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  8. Juan C. Scaiano
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Corresponding authors

Correspondence to M. Luisa Marin, Emilio I. Alarcon or Juan C. Scaiano.

Additional information

Electronic supplementary information (ESI) available: Details of material preparation and characterization. Cell culture details; tests involving films. See DOI: 10.1039/c4pp00404c

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Saez, S., Fasciani, C., Stamplecoskie, K.G. et al. Photochemical synthesis of biocompatible and antibacterial silver nanoparticles embedded within polyurethane polymers. Photochem Photobiol Sci 14, 661–664 (2015). https://doi.org/10.1039/c4pp00404c

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  • DOI: https://doi.org/10.1039/c4pp00404c

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