Issue 24, 1993
From the journal:

Journal of the Chemical Society, Chemical Communications

Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C1–C8δ-lactone subunit

Ian Paterson  and  Stephen P. Wren  

Abstract

The stereoselective, boron-mediated, aldol/reduction sequence, 4+5→8→9, allows an efficient asymmetric synthesis of the δ-lactone-containina. C1–C8 subunit 2 of discodermolide 1.

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Article information

DOI
https://doi.org/10.1039/C39930001790
Article type
Paper

J. Chem. Soc., Chem. Commun., 1993, 1790-1792

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Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C1–C8δ-lactone subunit

I. Paterson and S. P. Wren, J. Chem. Soc., Chem. Commun., 1993, 1790 DOI: 10.1039/C39930001790

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